Table 1.
Demographics and descriptive statistics for the GWAS sample, N = 7045
| Males | Females | P* | Total | |
|---|---|---|---|---|
| N (%) | 3140 (44.6) | 3905 (55.4) | - | 7045 (100) |
| Age, M (SD) | 54.4 (15.1) | 54.9 (14.4) | 0.51 | 55.7 (14.8) |
| SNAP, M (SD) | 11.3 (7.2) | 10.3 (6.2) | 6.2 × 10−11 | 10.7 (6.6) |
| SNCV, M (SD) | 50.0 (5.7) | 54.0 (6.0) | 1.8 × 10−166 | 52.2 (6.2) |
| Chronic pain, N (%) | 181 (5.8) | 376 (9.6) | 1.7 × 10−9 | 557 (7.9) |
N = 6879 with SNAP (sural nerve action potential, amplitude, μV) and N = 6979 with SNCV (sural nerve conduction velocity, m s−1), chronic pain (≥3 months, by self-report). M mean, SD standard deviation *Significance tests: Chi-square test for chronic pain and two-sided t-test for age, SNAP, and SNCV