Table 2.
Tests | EffectS | CIS | P S | P het | EffectL | CIL | P L | N (by gt) | P het |
---|---|---|---|---|---|---|---|---|---|
Additive | −0.49 | (−0.63, −0.34) | 1.1 × 10−11 | −0.26 | (−0.33, −0.19) | 1.5 × 10−12 | 10/172/6697 | ||
Males | −0.48 | (−0.67, −0.29) | 8.0 × 10−7 | −0.25 | (−0.37, −0.17) | 1.8 × 10−7 | 7/88/2974 | ||
Females | −0.51 | (−0.72, −0.30) | 1.5 × 10−6 | 0.83 | −0.27 | (−0.34, −0.16) | 3.0 × 10−7 | 3/84/3723 | 0.78 |
Recessive | −1.54 | (−2.16, −0.90) | 1.7 × 10−6 | −0.81 | (−1.12, −0.48) | 9.5 × 10−7 | 10/6869 | ||
Males | −1.55 | (−2.29, −0.81) | 4.2 × 10−5 | −0.82 | (−1.20, −0.44) | 2.3 × 10−5 | 7/3062 | ||
Females | −1.51 | (−2.65, −0.37) | 9.7 × 10−3 | 0.95 | −0.77 | (−1.38, −0.16) | 0.014 | 3/3807 | 0.89 |
Ht vs NC | −0.42 | (−0.57, −0.26) | 5.9 × 10−8 | −0.23 | (−0.32, −0.15) | 1.8 × 10−8 | 172/6697 | ||
Hm vs NC | −1.54 | (−2.16, −0.92) | 9.9 × 10−7 | −0.81 | (−1.13, −0.49) | 7.5 × 10−7 | 10/6697 | ||
Hm vs Ht | −1.12 | (−1.76, −0.48) | 5.8 × 10−4 | −0.61 | (−0.98, −0.26) | 6.0 × 10−4 | 10/172 |
Shown are associations with standardized (S) and and log transferred (L) SNAP. Effect difference between males and females was tested for statistical heterogeneity with a Q-test (Phet)19 (Methods).
EffectS in standard deviations (SD), EffectL in log(μV), 95% confidence interval (CI), Additive model (Additive), Recessive model (Recessive), Homozygotes (Hm), Heterozygotes (Ht), Non-carriers (NC). Sample size (N) by genotype (gt)