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. 2019 Apr 16;20:22. doi: 10.1186/s10195-019-0527-1

Table 7.

Comparison of rewiews

Papakostidis et al. Yin et al. Yin et al. Our study
Characteristics
Study period 1989–2012 1995–2013 1995–2015 2008–2018
Number of evaluated studies 37 16 24 27
Number of patients 898 303 590 619
Long bone involved Tibia + femur Tibia Tibia + femur Tibia
Study types 1 PC, 1P, 1 R, 34 RC nr 1 PC, 22 R, 1 RC 6 PC, 15 R, 6 RC
Mean age (range) 34.85 34.44 (25–44) 34.11 (nr) 36.1 (13–89)
Mean follow-up (range) (months) 43.81 44.37 (13–99) 32.49 (nr) 34.05 (6–122)
Mean bone union rate (range) (%) 94.3 (92–96.6) 96.69 (87–100) 97.26 (nr) 90.24 (77–100)
Bone results excellent + good (%) nr 87.52 88.76 88.8
Functional results excellent + good (%) nr 76 76.70 82.6
EFT (months) nr 9.19 9.41 10.75
EFI (months/cm) nr 1.46 1.64 1.74
Mean previous operative procedures (range) 3.46 nr 3.84 3.44
Infection etiology (%) 60.61 100 97.26 88.8
Mean bone defect (range) (cm) 7.37 6.01 (3.5–10.7) 6.54 (nr) 6.58 (1.6–20)
Complications
Complications (per patient) nr 1.47 1.23 1.22
Refracture (%) 5 nr 4 4
Amputation (%) 2.9 nr 4 1
Malunion (%) 5.7 nr 7 8.41
Recurrent Infection (%) nr nr 5 4.58
Pin tract infection (%) nr nr nr 46.6

nr not reported, PC prospective cohort, P prospective, RC retrospective cohort, R retrospective