Table 4.

Firth's bias-reduced penalized-likelihood logistic regression to predict a pCR.

Parameters	Odds ratio	95% C.I. of odds ratio	p value
Age (yrs)
<50	2.894	1.207–7.898	0.016
≥50	1
Subtype
Luminal A	0.080	0.001–0.684	0.016
Luminal B (HER-2 negative)	0.177	0.049–0.547	0.002
Luminal B (HER-2 positive)	0.835	0.294–2.321	0.729
HER-2 overexpression	0.818	0.276–2.339	0.708
Triple-negative	1

Abbreviations: pCR: pathological complete response; HER-2: human epidermal growth factor receptor 2.