Table 1.
Summary of subjects in behavioral studies of Experiment 2
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
|---|---|---|---|---|---|---|---|---|
| Cannulae targets | aHipp/25/32 | aHipp/25/32 | aHipp | aHipp/25/32 | aHipp/25/32 | aHipp | aHipp/25/32 | aHipp/25/32 |
| Human intruder test (Experiment 2a) | ||||||||
| Saline 1 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ||
| aHipp LY/CGP | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ||
| Saline 2 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ||
| Unpredictable threat test (Experiment 2b) | ||||||||
| aHipp saline | ✓ (2) | ✓ (4) | ✓ (1) | ✓ (2) | ✓ (1) | ✓ (1) | ||
| aHipp LY/CGP | ✓ (4) | ✓ (5) | ✓ (2) | ✓ (1) | ✓ (3) | |||
| aHipp LY/CGP & musbac 25 | ✓ (1) | ✓ (1) | ✓ (3) | ✓ (2) | ||||
| aHipp LY/CGP & musbac 32 | ✓ (6) | ✓ (3) | ✓ (4) | ✓ (4) | ||||
| musbac 25 | ✓ (3) | ✓ (6) | ✓ (5) | ✓ (3) | ||||
| musbac 32 | ✓ (5) | ✓ (2) | ✓ (6) | ✓ (2) | ✓ (4) | |||
| No. of infusions | ||||||||
| aHipp | 10 | 10 | 5 | 10 | 10 | 6 | 14 | 4 |
| Area 25 | 3 | 4 | NA | 3 | 3 | NA | 8 | 3 |
| Area 32 | 6 | 3 | NA | 2 | 4 | NA | 6 | 1 |
Checkmarks indicate that the subject took part in that phase of the study. For Experiment 2a, the numbers in parentheses indicate the order in which the infusions were received. Subjects 3 and 6 only had cannulae targeting the aHipp because they underwent prefrontal microdialysis (not reported here). Postmortem histology for subject 5 revealed that the cannulae were not located in areas 25 or 32 and histology for subject 7 revealed that the cannulae were not located in area 25; therefore, their data for these regions are excluded. However, the overall number of infusions that they received in these areas is included for completeness (including other drug combinations that are not reported here).