Table 1.
Licensed mucosal vaccines
| Target | Pathogen | Trade name | Delivery route (form) | Formulation (±adjuvant) |
|---|---|---|---|---|
| Human | Vibrio cholerae | Dukoral® | Oral (liquid) | Inactivated (recombinant cholera toxin subunit B) |
| ShanChol®, Euvichol® | Oral (liquid) | Inactivated | ||
| Vaxchora® | Oral (liquid) | Live attenuated | ||
| Influenza type A and B virus | FluMist™ | Intranasal (spray) | Live attenuated | |
| Poliovirus | Biopolio™ B1/3, and other oral polio vaccines – OPVs | Oral (liquid) | Live attenuated | |
| Rotavirus | Rotarix® and RotaTeq® | Oral (liquid) | Live attenuated | |
| Salmonella typhimurium | Typhi Vivotif® | Oral (capsules) | Live attenuated | |
| Adenovirus | Not trade name | Oral (tablets) | Live attenuated | |
| Approved for military | ||||
| Animal | Rabies virus | RABORAL‐V‐RG | Oral (bait) | Recombinant (Vaccinia virus vector) |
| Bovine parainfluenza 3 | Rispoval | Intranasal (spray) | Live attenuated | |
| bovine respiratory syncytial virus | ||||
| Bordetella bronchiseptica | Nobivac® | Intranasal (drops) | Live | |
| Canine parainfluenza virus | ||||
| Newcastle disease virus | Avinew NeO™ | Oral, ocular or nasal (spray, drinking water or drops) | Live attenuated |