Figure 4.

High frequencies of Ki67⁺ natural killer (NK) cells are associated with autoantibody production and B cell expansions. (a) Frequency of Ki67⁺ NK cells in systemic lupus erythematosus (SLE) patients grouped based on the presence (yes) or absence (no) of the indicated autoantibody [anti‐extractable nuclear antigen (ENA)]. Middle bar denotes median; surrounding bars denote first and second interquartile ranges. (b,d) Linear regression analysis of the frequency of plasma cells (b), CD95⁺ B cells (c), CD11c^hi B cells versus the frequency of Ki67⁺ NK cells in SLE patients. Statistical analyses performed using Pearson’s correlation.