Figure 10.

Increased NID1 expression is associated with poor prognosis in CRC patients. (A–F) Associations of NID1 expression with relapse-free survival in the indicated CRC patient cohorts. The statistics were calculated using the log-rank test. (G–J) Associations of NID1 expression with (G and I) tumor stage and the (H and J) CMS of CRC in the (G and H) TCGA COAD + READ and the (I and J) GSE39582 CRC patient cohorts. (K and L) Associations of NID1 DNA methylation with (K) tumor stage and the (L) CMS in the TCGA COAD + READ patient cohort. (G–L) Individual data points and means ± SD are provided. (G, I, and K) Significance was determined using 1-way analysis of variance with a post-test for linear trend. RSEM, RNA-Seq by Expectation Maximization.