Food Toxins
|
Food Source
|
Targets
|
Treatment Conditions
|
Main Findings
|
Ref.
|
Arsenic |
Rice, vegetables, seafood |
Neurotoxicity |
In vivo, rat, TQ: 10 µM
|
The neurotoxicity decrease was due to antioxidant potential of TQ |
5
|
Testicular Toxicity |
In vivo, rat, TQ: 10 mg/kg/d
|
TQ could protect against arsenic-induced testicular injury. |
6
|
Renal Failure |
In vivo, rat, TQ: 10 mg/kg/d
|
TQ plays a protective role against arsenic-induced toxicity in the kidney. |
7
|
Neurotoxicity |
In vivo, rat, TQ: 10 mg/kg/d
|
TQ can reduce the neurotoxic effect of arsenate. |
8
|
Cadmium |
Shellfish, mushroom , grains |
Hepatotoxicity |
In vivo, mice, TQ: 10 µM
|
TQ protected against cadmium-induced through its antioxidant oxidative stress. |
9
|
Mercury |
Fish |
Nephrotoxicity |
In vivo, rat, TQ, 10 mg/kg/d
|
Antioxidant effect of TQ prevents acute renal failure due to mercury toxicity. |
10
|
- |
- |
Nephrotoxicity |
In vivo, rat, TQ (5 mg/kg/d, per os);
|
Protective effect of TQ against Pb-induced renal antioxidant capacity impairment |
11
|
Neurotoxicity |
In vivo, rat, TQ:20 mg/kg b.w
|
TQ decreased the incidence of lead acetate-induced pathological lesions. |
12
|
Aluminum (AL chloride) |
Air, but not in its metallic form, in the food industry, drinking water, pharmaceutica and cooking utensils. |
Cerebellar toxicity |
In vivo, rat, NS oil:(1 ml/kg) orally
|
N. sativa may play a protective role against Al-induced cerebellar toxicity in humans.
|
13
|
Iron |
Water, iron supplement |
Hematotoxicity |
In vivo, Rabbit N. Sativa and Oriental Spices
|
N. sativa can be effective for health protection and health enhancement of organism.
|
14
|
Reduce toxicity |
In vivo, rat, TQ: 0.005M
|
TQ can inhibit the toxicity of some metals. |
15
|
Chromium |
Leather tanning, electroplating and stainless steel industries |
Genotoxicity |
In vivo, Tilapia and Zebrafish crude extract Nile of N. sativa:0.5 mg/kg
|
Inhibition may be mediated through antioxidant activity and inhibition of Cr(VI) enzymatic activation. |
16
|
Reduce toxicity |
In vivo. Rat, TQ: 500 µM
|
TQ can be beneficial for eliminating Cr(VI) toxicity |
17
|