Table 4.

Detection of the deletion (E746_A750delELREA) in EGFR by SViCT and compared tools in the SeraCare reference data set

Replicate	Dilution	SViCT	Lumpy2	GridSS	Socrates	Delly2	Pindel
1–2	5%	Yes	No	No	No	Yes*	Yes
1–2	1.2%	Yes	No	No	No	No	Yes*
1	0.6%	Yes	No	No	No	No	No

Only SViCT was able to detect this deletion at all dilutions with a detectable signal (0.1% does not contain breakpoint spanning reads). An asterisk (*) marks cases where the tool only found the deletion in one of two replicates.