Figure 1.

SEMA3E is reduced in patients with active ulcerative colitis (UC) patients and negatively correlated with immune markers. (a) mRNA levels of SEMA3E in active UC patients (n = 7) and healthy individuals (n = 9). Each value represents mean ± SEM. (b) Correlation between SEMA3E and pro‐inflammatory cytokines (IL1β, IL6, and TNF‐α). (c) Correlation between SEMA3E, CD11c ⁺ and CD86, or IL12A and IL23A. mRNA levels were quantified using RT‐qPCR. Student's t test and Spearman's correlation were applied (*P < 0.05)