Figure 2.

Sema3e is reduced during the progression of acute colitis and is associated with the expression of immune markers. Colon samples were obtained from Sema3e ^+/+ and Sema3e ^−/− C57Bl/6 mice. Colitic mice were treated with 5% dextran sulfate sodium (DSS) in the drinking water for 5 days; non‐colitic mice received only drinking water and served as control groups. Colonic mRNAs levels of (a) SEMA3E, (b) CD11c, and (c) CD86. mRNA levels were quantified using RT‐qPCR. Each value represents mean ± SEM from n = 6 per group (*P < 0.05). # refers to a significance when compared with control. One‐way ANOVA followed by multiple comparison test was applied