Table 1.

Thermodynamic parameters for the binding of histone H3 peptide variants to ASF1 as determined by ITC (see Figure 3 for details)

Peptide	K d [μm]	ΔG [kcal m −1]	N*	ΔH [kcal m −1]	TΔS [kcal m −1]
H3118–135	1.34±0.33	−8.0±0.14	0.94±0.04	−14.4±0.37	−6.4±0.51
H3118–135(St120–124)	0.86±0.11	−8.3±0.07	0.97±0.01	−15±0.96	−6.7±1.03
H3118–135(St123–127)GCA	1.6±0.13	−7.3±0.05	0.97±0.01	−4.2±0.08	3.1±0.2