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. 2019 Mar 4;47(7):3344–3352. doi: 10.1093/nar/gkz151

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© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Operon sequence features. Distribution of (A) intergenic distances, (B) gene pair conservation, (C) intergenic GC content, (D) RNA structure similarity (Pearson’ correlation coefficient) among operon and non-operon gene pairs. (E) Position specific mRNA folding energy mean margin between gene pairs in absolute values. The bars represent the position specific P-value (-log₁₀pv) comparing the OPs mean value to that of NOPs. The scale for the bar charts is not given, instead the common significance threshold is drawn (see legend). All P-values were computed using an unsupervised standard permutation test (see ‘Materials and Methods’ section: Permutation test). All significant P-values were confirmed using the Benjamini & Hochberg False Discovery Rate (FDR) procedure (62), = 137, = 76.

Inline graphic — Operon sequence features. Distribution of (A) intergenic distances, (B) gene pair conservation, (C) intergenic GC content, (D) RNA structure similarity (Pearson’ correlation coefficient) among operon and non-operon gene pairs. (E) Position specific mRNA folding energy mean margin between gene pairs in absolute values. The bars represent the position specific P-value (-log₁₀pv) comparing the OPs mean value to that of NOPs. The scale for the bar charts is not given, instead the common significance threshold is drawn (see legend). All P-values were computed using an unsupervised standard permutation test (see ‘Materials and Methods’ section: Permutation test). All significant P-values were confirmed using the Benjamini & Hochberg False Discovery Rate (FDR) procedure (62), = 137, = 76.