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. 2019 Mar 13;5(1):24. doi: 10.3390/ncrna5010024

Figure 2.

Figure 2

Diagrammatic representation of the genome structure of oncogenic viruses. MDV genome structure showing the locations of Meq and miRNAs including the miR-155 homolog miR-M4. KSHV genome structure with positions of miRNAs including the miR-155 homolog miR-K11 is shown for comparison. EBV genome showing the positions of genes such as EBNA2 and LMP1 that can modulate the expression of miR-155 are shown. Provirus structures of ALV with the 5′ and 3′ LTR involved in the insertional activation of bic/miR-155 and REV with the transduced v-rel oncogene are also shown.