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Conserved mechanisms of transformation by oncogenic viruses using miR-155 pathway. Expression of viral homologs of miR-155 (MDV-miRM4, and KSHV-miR-K11), activation of miR-155 expression through virus-encoded/transduced oncoproteins (EBV-encoded EBNA2, LMP1, and REV-transduced v-rel) and direct insertional activation of bic gene by avian leukosis virus (ALV) provirus.
