Table 1.

Factors influencing the radiation technique and fractionation schemes in the treatment of painful bone metastases in clinical practice.

Patient-Related Factors	Tumour-Related Factors	Logistic Issues
Performance status Patient’s mobility Clinical circumstances painful uncomplicated bone metastases pathologic fractures spinal cord compression re-irradiation Compliance to treatment Life expectancy Socioeconomic status Patient’s preferences Pain intensity	Histologic type of primary tumour Time elapsed from primary diagnosis to bone metastases Multiplicity of metastases Time of developing pain or neurologic deficits before RT 1	Treatment duration Significance of family members’ assistance Hospital location Distance from patient’s home to radiation therapy department Cost of therapy Reimbursement issues Organization of radiation departments Availability of multidisciplinary tumour board

¹ Radiation therapy.