Gene Ontology, KEGG pathway and PPI network analysis of the DEGs in OSCC. (A) Significantly enriched GO terms of DEGs in OSCC. GO analysis of the DEGs in 3 categories (biological process, cellular component and molecular function). (B) Significantly enriched pathway terms of DEGs in OSCC. (C) Complex PPI network and modular analysis. Using the Search Tool for the Retrieval of Interacting Genes online database, a total of 16 DEGs were filtered and included in the PPI network complex. The different colors indicated the different degree centralities. The underlined genes were hub genes identified. GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; DEG, differentially expressed gene; PPI, protein-protein interaction; OSCC, oral squamous cell carcinoma.