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. 2019 Mar 23;8(3):280. doi: 10.3390/cells8030280

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© 2019 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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MP101 and MP201 are protective for hearing loss due to noise trauma. The compound action potential (CAP) amplitude is plotted on a logarithmic on the y-axis with the intensity of noise (decibels) on the x-axis. The CAP input/output functions are shown at (a) 12, (b) 16, (c) 20 and (d) 24 kHz. The data indicate that the CAP amplitudes were larger (better) in the noise-exposed groups that received MP201, versus the Noise alone group and statistically significant at 16, 20 and 24 kHz (p-value < 0.0001), but not 12 kHz (unpublished). Repeat measures by ANOVA.