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. 2018 Dec 28;5(1):2. doi: 10.3390/ncrna5010002

Figure 3.

Figure 3

FOXA2 gene neighboring LINC00261 is co-downregulated in lung cancer. (A) The FOXA2/LINC00261 gene locus on the small arm of human chromosome 20. Black boxes indicate coding exons and white boxes indicate non-coding exons. The accession numbers for reference transcripts are indicated. (B–D) The FOXA2 expression data from LUAD-Korea (n = 77 normal/83 tumor), (B) LUAD-TCGA (n = 55 normal/486 tumor), and (C) the LUSC-TCGA (n = 17 normal/220 tumor). (D) Datasets are represented as box plots. (E) FOXA2 expression is significantly low in progressed/recurred LUAD tumor samples described in Table 1. (F,G) Kaplan–Meier Plot showing the association of FOXA2 expression or (F) LINC00261/FOXA2 expression with (G) patient survival in LUAD (all stages). p-value refers to log-rank p-value.