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. 2019 Mar 13;11(3):359. doi: 10.3390/cancers11030359

Figure 4.

Figure 4

In vivo experiments: GLPG1790-modified tumour growth of GBM cells subcutaneously injected in female nu/nu mice (xenograft model). In vivo efficacy of single dose (30 mg/Kg/day) of GLPG1790 compared with standard RT (1 dose of 4 Gy), chemo (TMZ, 16 mg/kg for 5 consecutive days) and chemo and radio (4 Gy + 16 mg/kg TMZ) therapy. (A) Percentage of mice in progression plotted for the time by using Kaplan–Meyer analysis for U87MG cell model. (B) Percentage of mice in progression plotted for the time by using Kaplan–Meyer analysis for U251 cell model. (C) Percentage of mice in progression plotted for the time by using Kaplan–Meyer analysis for T98G cell model. (D) Forrest plot analysis. In Table S1, we summarised the statistical analysis of xenograft experiments.