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. 2019 Feb 26;11(3):276. doi: 10.3390/cancers11030276

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Napabucasin abolishes clonogenic growth in biliary tract cancer cells. (A) Quantification of clonogenic growth of HuCCt-1 cells after 144 h napabucasin incubation (left) and as a time-resolved analysis of the same wells (right). Exemplary confluence images after 144 h of napabucasin are shown in the lower part. (B) Quantification of clonogenic growth of NOZ cells after 144 h napabucasin incubation (left) and as a time-resolved analysis of the same wells (right). Exemplary confluence images after 144 h of napabucasin are shown in the lower part. Data are presented as mean value ± SEM related to untreated control cells of at least three individual biological replicates. * indicates significant (p < 0.05) and ** highly significant (p < 0.01) results.