Table 1.

Binding energy components of 4.1G-CTD/NuMA obtained from the molecular mechanics Poisson-Boltzmann surface area method (MM-PBSA) calculation using the g_mmpbsa [45] in GROMACS.

	Binding Energy Components (kJ/mol)
ΔEvdW	−206.2 ± 2.2
ΔEele	−1496.4 ± 8.9
ΔGpolar	1653.3 ± 11.9
ΔGnonpolar	−36.9 ± 0.2
ΔGbind	−86.0 ± 4.7