Table 3.
Stool metabolites associated with binary ASQ communication score category.
| Metabolite | Super Pathway | Sub Pathway | HMDB ID | OR (95% CI) | p-Value |
|---|---|---|---|---|---|
| salicylate * | Xenobiotics | Drug | HMDB01895 | 0.3 (0.13,0.64) | 0.003 |
| R-mevalonate 5-diphosphate * | Lipid | Mevalonate Metabolism | HMDB01981 | 0.38 (0.18,0.69) | 0.004 |
| N-acetylglutamine * | Amino Acid | Glutamate Metabolism | HMDB06029 | 0.25 (0.09,0.65) | 0.005 |
| 2-hydroxyphenylacetate | Amino Acid | Tyrosine Metabolism | HMDB00669 | 0.44 (0.22,0.83) | 0.014 |
| suberate (octanedioate) * | Lipid | Fatty Acid, Dicarboxylate | HMDB00893 | 0.31 (0.12,0.78) | 0.015 |
| 2-aminophenol | Amino Acid | Tryptophan Metabolism | - | 0.43 (0.21,0.85) | 0.016 |
| cadaverine * | Amino Acid | Lysine Metabolism | HMDB02322 | 0.55 (0.33,0.89) | 0.017 |
| N-acetyl-3-methylhistidine | Amino Acid | Histidine Metabolism | - | 0.57 (0.34,0.96) | 0.034 |
| N-formylanthranilic acid | Amino Acid | Tryptophan Metabolism | HMDB04089 | 0.38 (0.15,0.93) | 0.039 |
| cis-4-hydroxycyclohexylacetic acid | Amino Acid | Tyrosine Metabolism | HMDB00451 | 0.54 (0.29,1.00) | 0.043 |
| 2,3-dimethylsuccinate | Amino Acid | Leucine, Isoleucine and Valine Metabolism | - | 0.55 (0.31,1.00) | 0.044 |
| S-1-pyrroline-5-carboxylate | Amino Acid | Glutamate Metabolism | HMDB01301 | 0.55 (0.30,1.00) | 0.048 |
| N-acetylserotonin | Amino Acid | Tryptophan Metabolism | HMDB01238 | 0.50 (0.24,0.97) | 0.050 |
* Significant in the 3 category communication score analysis.