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ANO6-induced cell death. Scheme summarizing the contribution of ANO6 to different regulated cell death pathways such as apoptosis, necroptosis, pyroptosis, and ferroptosis. Anoctamins may contribute to regulated cell death by cell shrinkage (apoptosis), increase in compartmentalized intracellular Ca2+ (all cell death pathways), or cell swelling, scrambling, blebbing, and membrane disintegration (ferroptosis, pyroptosis). For further details and references, see main text.
