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. 2019 Mar 25;8:12. Originally published 2019 Jan 3. [Version 2] doi: 10.12688/f1000research.17500.2

Figure 2. Comparison of the in vivo anti-infective potential of water extract and hydroalcoholic extract of P. guajava leaf extracts prepared by Microwave Assisted Extraction method, against five different pathogenic bacteria.

Figure 2.

Figures A– E shows data against P. aeruginosa, S. aureus, S. marcescens, C. violaceum and S. pyogenes respectively. Catechin (50 μg/mL) employed as a positive control conferred 100% protection on worm population against all the pathogenic bacteria except S. pyogenes. Against S. pyogenes, catechin could not offer any protection to host worms. Gentamicin (0.1 μg/mL) allowed survival of worm population to the extent of 80% in face of P. aeruginosa, S. aureus, or S. pyogenes challenge; and 100% against the remaining two pathogens. DMSO present in the ‘vehicle control’ at 0.5%v/v did not affect virulence of the bacteria towards C. elegans. DMSO (0.5%v/v) and GLE at tested concentrations showed no toxicity towards C. elegans.