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. 2019 Mar 6;11(3):320. doi: 10.3390/cancers11030320

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Kaplan-Meier curves based on nuclear Cx43 expression detected by immunohistochemistry of lung cancer samples. Tumours with significant nuclear Cx43 expression (over 5% of total tumours) are depicted in red and compared with the rest of the tumour samples (in blue). p-values refer to the log-rank test (Mantel-Cox analysis). Average survival times of the patient cohorts are listed. (a) NSCLC (non-small cell lung cancer, refers to the merged LUAD and LUSC groups); (b) LUSC (lung squamous cell carcinoma); (c) LUAD (lung adenocarcinoma).