Table 1.
Summary of fold-changes in connexin mRNA expression in lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) compared with normal healthy tissue.
| Regulation | Cx | Gene | LUAD | LUSC |
|---|---|---|---|---|
| Up | Cx46 | GJA3 | 1.74 | 35.6 |
| Cx59 | GJA9 | 3.01 | 1.82 | |
| Cx26 | GJB2 | 14.4 | 63.5 | |
| Cx31 | GJB3 | 3.27 | 34.4 | |
| Cx30.3 | GJB4 | 1.88 | 29.4 | |
| Cx31.1 | GJB5 | 1.66 | 59.9 | |
| Cx30 | GJB6 | 7.47 | 289 | |
| Down | Cx37 | GJA4 | 0.36 | 0.18 |
| Cx40 | GJA5 | 0.32 | 0.17 | |
| Cx50 | GJA8 | 0.83 | 0.97 | |
| Cx45 | GJC1 | 0.67 | 0.76 | |
| Cx47 | GJC2 | 0.325 | 0.234 | |
| Cx30.2 | GJC3 | 0.817 | 0.61 | |
| Cx31.9 | GJD3 | 0.52 | 0.43 | |
| Cx40.1 | GJD4 | 0.89 | 0.96 | |
| Mixed | Cx43 | GJA1 | 0.31 | 1.33 |
| Cx32 | GJB1 | 1.49 | 0.064 | |
| Cx25 | GJB7 | 0.41 | 7.18 | |
| Cx36 | GJD2 | 0.56 | 2.9 |