Table 5.
Most significant metabolites reported over all the selected studies.
| Risk Prediction | Diagnosis | Prognosis | Recurrence | |
|---|---|---|---|---|
| citrate | Mondul et al. 2015 [15] (B) | Kumar et al. 2016 [22]) (B) | Giskeødegård et al. 2013 [52] (T) | |
| Huang et al. 2017 [16] (B) | Weis et al. 2017 [65] (O) | Sandsmark et al. 2017 [54] (T) | ||
| Roberts et al. 2017 [63] (O) | Nagarajan et al. 2015 [67] (O) | Selnæs et al. 2013 [53] (T) | ||
| Wang et al. 2010 [69] (O) | Hansen et al. 2016 [55] (T) | |||
| Zhang et al. 2014 [59] (T) | Meller et al. 2016 [57] (T) | |||
| Keshari et al. 2011 [58] (T) | ||||
| Thysell et al. 2010 [29] (T) | ||||
| glycine | de Vogel et al. 2014 [18] | Kumar et al. 2015 [21] (B) | Hansen et al. 2016 [55] | |
| Kumar et al. 2016 [22] (B) | ||||
| Pérez-Rambla et al. 2017 [37] (U) | ||||
| Struck-Lewicka et al. 2015 [38] (U) | ||||
| Liu et al. 2015 [46] (T) | ||||
| Jung et al. 2013 [47] (T) | ||||
| Giskeødegård et al. 2013 [52] (T) | ||||
| glycerol-3-phosphate | Andras et al. 2017 [20] (B) | McDunn et al. 2013 [44] (T) | ||
| Sreekumar et al. 2009 [28] (T) | Thysell et al. 2010 [29] (T) | |||
| glycerophosphocholine | Andras et al. 2017 [20] (B) | Giskeødegård et al. 2013 [52] (T) | ||
| Keshari et al. 2011 [58] (T) | ||||
| Zhang et al. 2014 [59] (T) | ||||
| alanine | Kumar et al. 2015 [21] (B) | Kumar et al. 2015 [21] (B) | ||
| Kumar et al. 2016 [22] (B) | Zhang et al. 2014 [59] (T) | |||
| Struck-Lewicka et al. 2015 [38] (U) | ||||
| Shuster et al. 2011 [45] (T) | ||||
| Jung et al. 2013 [47] (T) | ||||
| Zhang et al. 2014 [59] (T) | ||||
| choline | Ren et al. 2016 [43] | Selnæs et al. 2013 [53] (T) | ||
| Shuster et al. 2011 [45] | Zhang et al. 2014 [59] (T) | |||
| Giskeødegård et al. 2013 [52] (T) | Nagarajan et al. 2015 [67] (O) | |||
| Keshari et al. 2011 [58] (T) | Kobuscet al. 2011 [68] (O) | |||
| Zhang et al. 2014 [59] (T) | ||||
| Weis et al. 2017 [65] (O) | ||||
| Wang et al. 2010 [69] (O) | ||||
| phosphocholine | Giskeødegård et al. 2013 [52] (T) | Zhang et al. 2014 [59] (T) | ||
| Keshari et al. 2011 [58] (T) | ||||
| Zhang et al. 2014 [59] (T) | ||||
| glycerophosphocholine | Andras et al. 2017 [20] (B) | Zhang et al. 2014 [59] (T) | ||
| Giskeødegård et al. 2013 [52] (T) | ||||
| Keshari et al. 2011 [58] (T) | ||||
| uracil | Huan et al. 2016 [42] (T) | |||
| Sreekumar et al. 2009 [28] (T) | ||||
| Shuster et al. 2011 [45] (T) | ||||
| Jung et al. 2013 [47] (T) | ||||
| McDunn et al. 2013 [44] (T) | ||||
| proline | Dereziński et al. 2017 [27] (B) | Sreekumar et al. 2009 [28] (T) | ||
| Jung et al. 2013 [47] (T) | Liu et al. 2015 [46] (T) | |||
| McDunn et al. 2013 [44] (T) | ||||
| histidine | Fernández-Peralbo et al. 2016 [35] (U) | |||
| Jung et al. 2013 [47] (T) | ||||
| spermine | Roberts et al. 2017 [63] (O) | Nagarajan et al. 2015 (O) | Liu et al. 2015 [46] (T) | |
| Weis et al. 2017 [65] (O) | Shuster et al. 2011 [45] (T) | |||
| Giskeødegård et al. 2013 [52] (T) | ||||
| Selnæs et al. 2013 [53] (T) | ||||
| Sandsmark et al. 2017 [54] (T) | ||||
| Hansen et al. 2016 [55] (T) | ||||
| Meller et al. 2016 [57] (T) | ||||
| Maxeiner et al. 2010 [ 60] (T) | ||||
| 2-aminoadipic acid | Jung et al. 2013 [47] (T) | |||
| Shuster et al. 2011 [45] (T) | ||||
| Sreekumar et al. 2009 [28] (T) | ||||
| Priolo et al. 2014 [48] (T) |
B: Blood, U: Urine, T: Tissue, O: Other.