Exercise partially prevents the loss of muscle mass and function in tumor-bearing mice. Muscle weight (A), grip strength test (B) and tissue weight (C) of control (n = 5), control exercised (control ex; n = 6) and tumor-bearing mice either sedentary (C26; n = 8) or exercised (C26 ex; n = 8). Tumor weight (D) of sedentary (C26; n = 8) or exercised mice (C26 ex; n = 8). Muscle and tissue weight (means ± SD) are expressed as percentage of control. Grip strength data (means ± SD) are expressed as the ratio of unit force (mN) and initial body weight (g). Tumor weight (means ± SD) is expressed in grams (g). Significance of the differences: * p < 0.05, ** p < 0.01, *** p < 0.001 vs. control; ##
p < 0.01, ###
p < 0.001 vs. control ex; $
p < 0.05, $$
p < 0.01 vs. C26.