Skip to main content
. 2019 Mar 26;8(3):285. doi: 10.3390/cells8030285

Figure 2.

Figure 2

Expression of IL-6R, IL-12R, and IL-23R in T, B, and NK cells. (A–E) mRNA level of IL-6ST (A), IL-6Rα (B), IL-12Rβ1 (C), IL-12Rβ2 (D), and IL-23R (E) in CD4+ T cells, CD8+ T cells, B cells, and NK cells of healthy controls (HC) and patients with RRMS. (F) Dot plot example of IL-6Rα+ lymphocytes; isotype control is shown in the upper panel. (G–J) Frequency of IL-6Rα+ CD4+ T cells (G), CD8+ T cells (H), B cells (I), and NK cells (J) in healthy controls and patients with RRMS. (K) Dot plot example of IL-12Rβ2+ lymphocytes; isotype control is shown in the upper panel. (L–O) Frequency of IL-12Rβ2+ CD4+ T cells (L), CD8+ T cells (M), B cells (N), and NK cells (O) in healthy controls and patients with RRMS. (P) Dot plot example of IL-23R+ lymphocytes; isotype control is shown in the upper panel. (Q–T) Frequency of IL-23+ CD4+ T cells (Q), CD8+ T cells (R), B cells (S), and NK cells (T) in healthy controls and patients with RRMS. The median value is shown for all groups analyzed.