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. 2019 Mar 26;8(3):285. doi: 10.3390/cells8030285

Figure 6.

Figure 6

No association between STAT3/4 MS risk alleles and STAT3/4-pY. (A–E) Frequency of IL-6-induced STAT3-pY+ resting CD4+ T cells (A), resting CD8+ T cells (B), resting B cells (C), primed CD4+ T cells (D), and primed CD8+ T cells (E) in donors homozygous (AA), heterozygous (AG), or negative (GG) for the STAT3 MS risk allele rs1026916. (F-J) Frequency of IL-12-induced STAT4-pY+ resting CD4+ T cells (F), resting CD8+ T cells (G), resting NK cells (H), primed CD4+ T cells (I), and primed CD8+ T cells (J) in donors homozygous (CC), heterozygous (AC), or negative (AA) for the STAT4 MS risk allele rs6738544. (K–O) Frequency of IL-23-induced STAT3-pY+ resting CD4+ T cells (K), resting CD8+ T cells (L), resting NK cells (M), primed CD4+ T cells (N), and primed CD8+ T cells (O) in donors homozygous (AA), heterozygous (AG), or negative (GG) for the STAT3 MS risk allele rs1026916. The median value is shown for all groups analyzed.