Figure 7.

Identification of different pro-peptide cleavage motifs in one precursor. (A) Pro-peptide cleavage motifs of CsTx-33, CsTx-35, and other peptides featuring a dibasic motif. The sequence parts shown include the ends of pro-peptides and the beginning of mature peptides. The start of the mature peptide sequences is indicated with a bold red line. Amino acids of the mature peptide are in bold. Potential protease cleavage motifs are displayed in dashed boxes. Red boxes indicate the cleavage motif, which directly locates the N-terminal of the experimentally found start of the mature peptide. (B) Sequence comparison of transcripts coding for CsTx-33 and other C. salei peptides with a similar N-terminal sequence of the mature peptide. Nucleotides differing between sequences are highlighted in red.