Table 1.
Fungal strains that were studied in depth for the production of beauvericin and beauvenniatin analogues. Host species, fungal strains identification based on internal transcribed spacers ITS1-ITS2 or translation elongation factor 1α gene (tef-1α) sequence analysis and comparison with reference sequences from the GenBank Database. Beauvericin and beauvenniatin analogues are identified relative to their production rates.
| Strain | Species | Host | Sequence Nucleotide Identity | Metabolic Profile * |
|---|---|---|---|---|
| RT 6.7 | Fusarium proliferatum | rice (Oryza sativa) | 99.78% identity to the Fusarium proliferatum acc. number JF740730.1 | beauvericin (87.0%), beauvericin A/F (0.8%), beauvericin D (3.5%), beauvenniatin A (0.8%), beauvenniatin L (3.2%), beauvericin J (4.7%), beauvericin K (trace) |
| RT 5.4 | Fusarium proliferatum | rice (Oryza sativa) | 99.78% identity to the Fusarium proliferatum acc. number JF740730.1 | beauvericin (95.6%), beauvericin D (2.6%), beauvenniatin L (0.8%), beauvericin J (0.9%) |
| MU12 | Fusarium verticillioides | banana (Musa L.) | 98.66% identity to the Fusarium verticillioides acc. number JF740717.1 | beauvericin (18.4%), beauvericin D (8.5%), beauvenniatin A (61.3%), beauvericin K (11.8%) |
| P35 | Fusarium concentricum | pineapple (Ananas comosus) | 100% identity to the Fusarium concentricum, acc. number JF740760.1 | beauvericin (77.9%), beauvericin A/F (2.2%), beauvericin D (3.6%), beauvenniatin A (3.6%), beauvenniatin L (8.6%), beauvericin J (4.1%), beauvericin K (trace), beauvericin L (trace) |
| PIN 5.5 | Fusarium proliferatum | unknown | 99.32% identity to the Fusarium proliferatum acc. number JF740730.1 | beauvericin (87.7%), beauvericin A/F (1.0%), beauvericin D (3.1%), beauvenniatin A (1.2%), beauvenniatin L (5.3%), beauvericin J (1.8%) |
| 4447 | Isaria farinosa | bark beetle (Trypodendron lineatum) | 100% identity to the Isaria farinosa, acc. number AY624181.1 | beauvericin (35.4%), beauvericin A/F (42.5%), beauvericin C (13.8%), beauvericin D (1.5%), beauvenniatin A (0.4%), beauvenniatin L (0.3%), beauvericin J (5.5%), beauvericin K (0.2%), beauvericin L (0.3%) |
* The relative peak areas ([M + NH4]+) of individual analogues as fractions of the total peak area of detected cyclodepsipeptides is shown in brackets.