Table 5.
Brain Regions Showing Statistically Reduced Task-Related Activation in EI Patients Compared to Matched Healthy Control Subjects When Performing Saccades to Predictable Versus Unpredictable Saccade Targets
| Left hemisphere | Right hemisphere | |||||
|---|---|---|---|---|---|---|
| Volume (mm3) of increased activation | Peak t value | X, Y, Z coordinates | Volume (mm3) of increased activation | Peak t value | X, Y, Z coordinates | |
| EI < healthy | ||||||
| Frontal eye fields | 2403 | 4.55 | −46, −4, 47 | 486 | 3.44 | 31, −4, 62 |
| Supplementary eye fields | 162 | 3.96 | −7, 1, 68 | 351 | 4.20 | 1, −4, 65 |
| Intraparietal sulcus | 2079 | 4.54 | −46, −46, 60 | |||
| Middle frontal gyrus | 3321 | 4.65 | −46, 34, 26 | 2295 | 4.55 | 25, −28, 41 |
| Precuneus | 54 | 2.61 | −13, −82, 38 | 1647 | 4.57 | 4, −55, 50 |
| Anterior cingulate cortex | 1404 | 4.10 | −4, 28, 14 | 1323 | 4.51 | 1, 19, 32 |
| Motor cingulate cortex | 243 | 4.21 | −10, 10, 32 | 27 | 1, 13, 29 | |
| Posterior cingulate cortex | 27 | 2.81 | −1, −46, 8 | 81 | 3.14 | 1, −46, 8 |
| Striatum | 189 | 3.29 | −28, −10, −1 | 27 | 2.61 | 28, −10, −3 |
| Insula | 2592 | 5.52 | −49, 1, −9 | 1296 | 4.13 | 31, 19, −1 |
| Thalamus | 27 | 2.85 | −10, −28, 2 | |||
The table shows the t value for the peak activation in each region, its corresponding Talairach coordinates, and volume of voxels showing statistically reduced activation in EI patients.