Table 2.
Dynamics of cytokines ejaculate and the results of questioning of patients with chronical abacterial prostatitis before and after treatment
| Indicator | Group 1, n = 42 | Group 2, n = 39 | ||
|---|---|---|---|---|
| Before treatment M ±SD | After treatment M ±SD | Before treatment M ±SD | After treatment M ±SD or Me (Q25–Q75) | |
| TNF-α (pg/ml) | 16.6 ±2.4 | 10.9 ±1.7* | 16.4 ±2.7 | 11.5 ±1.2* |
| IL-1β (pg/ml) | 118.8 ±7.1 | 89.6 ±10.9* | 121.8 ±7.1 | 98.8 ±10.3* |
| IL-8 (pg/ml) | 12.7 ±2.1 | 6.4 ±1.3* | 13.7±2.0 | 5.7 (5.1–8.0)* |
| IL-10 (pg/ml) | 154.1 ±17.9 | 203.9 ±15.4* | 178.3 ±13.2 | 184.3 ±22.9 |
| TGF-β (pg/ml) | 21.8 ±5.6 | 30.7 ±5.4* | 21.4 ± 4.3 | 23.0 ±3.8 |
| NIH-CPSI, points | 19.9 ±4.7 | 9.5 ±4.0* | 19.1 ±4.4 | 11.5 ±3.2* |
| PHQ-9, points | 13.7 ±2.6 | 4.7 ±2.3* | 13.1 ±2.8 | 8.9 ±3.2* |
TNF-α – tumor necrosis factor-α; IL-1β – interleukin-1β; IL-8 – interleukin-8; IL-10 – interleukin-10; TGF-β1 – transforming growth factor-β1; NIH-CPSI – NIH-Chronic Prostatitis Symptom Index; PHQ-9 – Patient Health Questionnaire-9
*
the difference before and after treatment which was statistically significant (p <0.05)