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. 2019 Mar 19;11(3):383. doi: 10.3390/cancers11030383

Table 1.

Central nervous system necrosis (n = 36 patients).

CNS Necrosis Patients %
Classification
Grade IV 1 2.8
Grade III 5 13.9
Grade II 13 36.1
Grade I 17 47.2
Localization
Temporal lobe 30 83.4
Frontal lobe 4 11.1
Other 2 5.5
Radiographic Response *
Grade IV n.a. n.a.
Grade III 4 80.0
Grade II 5 29.4
Grade I 4 16.0
Median Range
Time Interval
Grade IV n.a. n.a.
Grade III 16.6 8.7–32.5
Grade II 10.2 2.3–60.5
Grade I 9.2 2.8–75.0

* ≥25% reduction of the T2 alteration (axial diameter) on Magnetic Resonance Imaging (MRI).