Table 3.
Hazard ratio of chronic kidney disease according to prediabetes, body composition, and metabolic syndrome component
| Non-adjusted | Adjusted | |||
|---|---|---|---|---|
| Odds ratio (95% confidence interval) | P-value | Odds ratio (95% confidence interval) | P-value | |
| IGT | 1.362 (1.184–1.567) | < 0.001 | a1.135 (1.182–1.310) | 0.043 |
| Prediabetes defined by HbA1C | 1.661 (1.454–1.897) | < 0.001 | b1.391 (1.213–1.595) | < 0.001 |
| Baseline eGFR (60–89 vs. ≥90) | 4.704 (3.499–4.744) | < 0.001 | b3.727 (3.184–4.363) | < 0.001 |
| Male sex | 2.136 (1.848–2.469) | < 0.001 | b2.310 (1.993–2.77) | < 0.001 |
| Age > 65 years | 3.347 (2.878–3.892) | < 0.001 | b1.918 (1.631–2.255) | < 0.001 |
| Current smoking | 1.121 (0.841–1.212) | 0.242 | ||
| BMI > 25 kg/m2 | 1.347 (1.180–1.539) | < 0.001 | b1.100 (0.954–1.269) | 0.190 |
| Hypertension | 2.104 (1.835–2.412) | < 0.001 | b1.606 (1.375–1.875) | < 0.001 |
| Regular activity | 0.853 (0.745–0.975) | 0.020 | b0.859 (0.751–0.983) | 0.027 |
| Metabolic syndrome | 1.318 (1.167–1.632) | 0.012 | b1.125 (0.943–1.341) | 0.191 |
BMI body mass index, eGFR estimated glomerular filtration, IGT impaired glucose tolerance
amultivariate analysis was done including IGT, baseline eGFR, age, BMI, hypertension, regular activity, metabolic syndrome
bmultivariate analysis was done including prediabetes defined by HbA1C, baseline eGFR, age, BMI, hypertension, regular activity, metabolic syndrome