Table 2.
Independent predictors of survival from a multivariate Cox proportional hazards model at the first and second rounds of TACE
| Variables | At the first TACE | At the second TACE | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Male gender | 1.09 (0.86–1.38) | 0.501 | – | – |
| Tumor size (cm) | < 0.001 | < 0.001 | ||
| ≤7 | 1 | 1 | ||
| >7 | 1.90 (1.53–2.36) | 1.91 (1.36–2.69) | ||
| Tumor number | < 0.001 | < 0.001 | ||
| Unifocal | 1 | 1 | ||
| Multifocal | 1.73 (1.43–2.09) | 1.78 (1.45–2.19) | ||
| Alpha-fetoprotein (ng/mL) | < 0.001 | < 0.001 | ||
| ≤400 | 1 | 1 | ||
| >400 | 1.58 (1.27–1.95) | 2.31 (1.63–3.28) | ||
| Total bilirubin (mg/dL) | 0.006 | 0.241 | ||
| ≤0.9 | 1 | 1 | ||
| >0.9 | 1.31 (1.08–1.58) | 1.14 (0.91–1.43) | ||
| Serum albumin (g/dL) | < 0.001 | 0.004 | ||
| ≥3.6 | 1 | 1 | ||
| <3.6 | 1.45 (1.19–1.77) | 1.39 (1.11–1.75) | ||
TACE; transarterial chemoembolization; HR, hazard ratio; CI, confidence interval