Table 1.
Patients’ baseline and tumor parameters
| Parameter | nCRT + S (n = 40) | dCRT (n = 55) | p-value |
|---|---|---|---|
| Age, (years) | |||
| Median | 65 | 68 | 0.079 |
| IQR | 56–72 | 62–74 | |
| Male sex | 22 (55%) | 40 (73%) | 0.085 |
| T-stage (cT) | |||
| Tis | 0 (0%) | 1 (2%) | 0.148 |
| T1 | 1 (3%) | 3 (5%) | |
| T2 | 7 (18%) | 8 (15%) | |
| T3 | 32 (80%) | 37 (67%) | |
| T4 | 0 (0%) | 6 (11%) | |
| N-stage (cN) | |||
| N+ | 40 (100%) | 47 (85%) | 0.019 |
| Grading | |||
| G1 | 1 (3%) | 0 (0%) | 0.729 |
| G2 | 20 (53%) | 26 (53%) | |
| G3 | 17 (45%) | 23 (47%) | |
| Tumor length, (cm) | |||
| Median | 5 | 5 | 0.445 |
| IQR | 3–7 | 4–7 | |
| Distance from dental arch to cranial tumor border, (cm) | |||
| Median | 26 | 20 | < 0.001 |
| IQR | 24–30 | 17–26 | |
| Tumor location | |||
| Cervical | 4 (10%) | 26 (47%) | < 0.001 |
| Thoracic | 35 (88%) | 28 (51%) | |
| Abdominal | 1 (3%) | 1 (2%) | |
| Cumulative RT dose, (Gy) | |||
| Median | 41.4 | 54 | < 0.001 |
| IQR | 41.4–45 | 54–59.4 | |
| Complete tumor resection | 36 (97%) | – | – |
IQR inter-quartiles-range, Gy Gray, RT radiotherapy