Table 3.

Univariate Cox regression analysis

Parameter	OS HR [95% CI]	p-value	PFS HR [95% CI]	p-value	LR HR [95% CI]	p-value
Treatment Regimen (nCRT + S vs. dCRT)	0.690 [0.377; 1.264]	0.230	0.643 [0.374; 1.107]	0.111	0.199 [0.068; 0.582]	0.003
Age (continuous)	1.025 [0.990; 1.061]	0.160	1.025 [0.994; 1.057]	0.115	1.009 [0.966; 1.053]	0.699
Sex (female vs. male)	0.830 [0.446; 1.545]	0.557	0.807 [0.462; 1.410]	0.451	0.775 [0.334; 1.80]	0.553
Tumor lengths, cm (continuous)	0.996 [0.899; 1.104]	0.946	1.012 [0.925; 1.107]	0.798	1.022 [0.895; 1.167]	0.744
Tumor location (continuous)	0.954 [0.907; 1.004]	0.069	0.940 [0.897; 0.985]	0.010	0.844 [0.773; 0.921]	< 0.001
T-stage (Tis/T1/2 vs. T3/4)	1.295 [0.618; 2.714]	0.493	0.966 [0.485; 1.924]	0.921	1.319 [0.524; 3.316]	0.557
N-stage (N0 vs N1)	1.780 [0.965; 4.560]	0.230	1.167 [0.464; 2.935]	0.743	1.207 [0.284; 5.136]	0.799
Grading (G1/2 vs. G3)	2.059 [1.084; 3.911]	0.027	1.673 [0.961; 2.912]	0.069	2.065 [0.882; 4.837]	0.095

IQR inter-quartiles-range, OS overall survival, PFS progression-free survival, LR local recurrence, HR Hazard ratio, CI Confidence interval