. 2019 Apr 16;19:67. doi: 10.1186/s12883-019-1285-7

Table 2.

Allele frequencies in cases and controls and odds ratio estimates for IS risk

SNP	Gene(s)	Band	Alleles A/B	MAF		HWE ^a p value	OR (95% CI)	^b p value
SNP	Gene(s)	Band	Alleles A/B	Case	Control	HWE ^a p value	OR (95% CI)	^b p value
rs3918249	MMP9	20q13.12	T/C	0.212	0.251	0.09	0.80 (0.59–1.07)	0.142
rs2274755	MMP9	20q13.12	T/G	0.116	0.131	0.011	0.88 (0.60–1.28)	0.500
rs3918254	MMP9	20q13.12	T/C	0.221	0.227	0.277	0.97 (0.72–1.30)	0.820
rs3787268	MMP9	20q13.12	A/G	0.442	0.371	0.134	1.34 (1.04–1.73)	0.022^*

SNP: single nucleotide polymorphism, Alleles A/B: Minor/Major alleles, MAF: minor allele frequency, OR: odds ratio, CI: confidence interval, HWE: Hardy–Weinberg equilibrium

^* p ≤ 0.05 indicates statistical significance

^a p was calculated by exact test

^b p was calculated by Pearson Chi-squared test