Table 1.
Patients’ main characteristics
| Patient | Gender | Age (years) | BMI | SAPS II (at ICU admission) | SOFA (day of study) | Etiology of acute respiratory failure | Days of intubation | ARDS (yes or no) | PaO2/FiO2(mmHg)* | PEEP (cmH2O)* | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 75 | 25 | 34 | 7 | Sepsis | 7 | Yes | 198 | 10 | Survivor |
| 2 | M | 79 | 26 | 33 | 8 | Thoracic trauma | 7 | Yes | 160 | 8 | Non-survivor |
| 3 | M | 90 | 29 | 46 | 7 | Sepsis | 1 | Yes | 205 | 10 | Survivor |
| 4 | M | 71 | 29 | 30 | 10 | Postoperative respiratory failure | 2 | No | 230 | 7 | Survivor |
| 5 | F | 80 | 35 | 22 | 9 | Postoperative respiratory failure pneumonia | 5 | Yes | 263 | 8 | Survivor |
| 6 | M | 69 | 33 | 30 | 4 | Postoperative respiratory failure | 2 | No | 168 | 8 | Survivor |
| 7 | M | 66 | 24 | 40 | 6 | Sepsis | 1 | No | 294 | 6 | Survivor |
| 8 | F | 85 | 19 | 38 | 5 | Septic shock | 1 | No | 273 | 7 | Survivor |
| 9 | F | 80 | 33 | 63 | 10 | Hemorrhagic shock | 4 | Yes | 256 | 10 | Survivor |
| 10 | F | 76 | 24 | 33 | 8 | Hemorrhagic shock | 2 | No | 258 | 7 | Non-survivor |
| 11 | F | 72 | 26 | 38 | 10 | Postoperative respiratory failure pneumonia | 6 | No | 175 | 6 | Survivor |
| 12 | F | 78 | 35 | 38 | 11 | Postoperative respiratory failure | 4 | No | 141 | 6 | Survivor |
| Median [IQR] | 5 M/7 F | 77 [71–80] | 28 [24–33] | 36 [31–40] | 8 ± [6.3–10] | 3 [1.3–5.8] | 5 yes/7 no | 218 [170–262] | 7.5 [6.3–9.5] | 2 non-survivors/10 survivors |
BMI body mass index, SAPSII simplified acute physiology score II, ICU intensive care unit, SOFA sequential organ failure assessment, ARDS acute respiratory distress syndrome, PaO2/FiO2 partial pressure of arterial oxygen on inspired fraction of oxygen ratio, PEEP positive end-expiratory pressure
*Before starting the protocol (clinical)