Fig. 2. LC-MS analysis (total ion current) of the reaction mixture for conversion of Bn-THPO (8) to Bn-THP^H (5) (strategy C) at (A) 0 h (B) 8 h (C) 48 h and (D) 72 h. RT: Retention time; MA: area; BP: m/z value. Insets: Bn-THPO and MS signal of [Bn-THPO + H]⁺ (purple), mono-substituted Bn-THPO and MS signal (green), di-substituted Bn-THPO and MS signal (blue), Bn-THP^H structure and MS signal (orange).