Fig. 6. (A) Dynamic PET/CT MIP of a mouse injected with acetate buffered 68Ga at time 0 followed by THPH at 30 min. Blood clearance of 68Ga acetate (represented by radioactivity in the heart ventricles) is slow in the first 30 min. After the injection of THPH a sudden clearance occurs through the kidneys into the bladder. (B) RadioHPLC of urine 60 min after 68Ga injection (method 3), showing only one peak, attributed to [68Ga(THPH)]. (C) Time/activity curves showing % ID in heart (as a measure of blood activity), kidneys and bladder as a function of time. Each data point represents a 5 min interval defined by its starting time.
