Table 2.

Unadjusted and aHRs for Cardiovascular Events in Subjects With AAD vs Matched Controls, Stratified by Sex

Outcome	AAD (n = 1500)		Controls (n = 13,758)		Crude HR	95% CI	P Value	aHRa	95% CI	P Value
	Events, n	Events/1000 PY	Events, n	Events/1000 PY
CVDb,c
All	94	10.7	563	7.0	1.52	1.21-1.89	0.003d	1.20	0.95-1.51	0.13
Male	40	10.3	270	7.6	1.35	0.97-1.88	0.08	1.05	0.74-1.50	0.79
Female	54	12.7	293	7.6	1.68	1.25-2.25	<0.001d	1.35	0.98-1.85	0.06
IHD
All	71	8.1	338	4.2	1,92	1.48-2.47	<0.001d	1.61	1.22-2.12	0.001d
Male	28	7.0	181	5.0	1.41	0.95-2.10	0.09	1.16	0.75-1.78	0.50
Female	43	9.8	157	3.9	2.50	1.79-3.51	<0.001d	2.15	1.49-3.10	<0.0001d
CeVD
All	44	5.0	343	4.3	1.17	0.85-1.60	0.33	0.88	0.63-1.23	0.46
Male	19	4.7	144	3.9	1.21	0.75-1.95	0.44	0.88	0.53-1.50	0.63
Female	25	5.6	199	4.9	1.14	0.75-1.73	0.53	0.88	0.56-1.37	0.57

^aAdjusted for diabetes and COPD.

^bCVD included IHD and CeVD.

^cNumber of events might not equal the sum of IHD and CeVD because both can occur in the same individual.

^dStatistically significant.