Table 2.
Statistically significant results for C1QA and C1QC variants and AO variation using GEE analysis, after Bonferroni corrections
| Genes | SNPs | Genotypes | B | 95% CI | P‐value |
|---|---|---|---|---|---|
| C1QA | Intercept | – | 39.1 | [35.7; 42.5] | <0.001 |
| rs201693493 | GG (Reference: 39.6) | – | – | – | |
| GA | 15.9 | [13.0; 18.7] | <0.001 | ||
| rs149050968 | CC (Reference: 39.6) | – | – | – | |
| CT | 10.1 | [7.0; 13.3] | <0.001 | ||
| C1QC | Intercept | – | 38.6 | [34.7; 42.5] | <0.001 |
| rs2935537 | GG (Reference: 39.8) | – | – | – | |
| GA | −6.9 | [−11.3; −2.4] | 0.003 | ||
| rs200952686 | GG (Reference: 39.7) | – | – | – | |
| GA | 31.9 | [28.7; 35.1] | <0.001 | ||
| rs201241346 | GG (Reference: 39.8) | – | – | – | |
| GA | −10.9 | [−14.0; −7.8] | <0.001 |
Reference: Mean AO; B, unstandardized coefficient (estimated quantitative effect of each genotype on mean AO variation, according to the intercept, compared with the reference genotype); CI, confidence interval; significance level was set to 0.05.