Fig. 2. Effect of Aibp2 on Srebp2 activity in ECs.
A. DNA constructs used to make the transgenic zebrafish with heat shock-induced Aibp2 expression. SS: secretion signal. B-C. qRT-PCR analyses of srebf1 and srebf2 in the AGM regions of Aibp2 overexpression (B) or knockdown zebrafish (C). D. Immunoblots of Srebp2 in HUVECs incubated with or without AIBP/HDL3 (μg/ml) for 4 hours. **, p<0.01. P: Srebp2 precursor; N: nuclear Srebp2.