Table II.
Altered expression profile of S100 proteins in various human pregnancy-related diseases
| Pregnancy-related diseases | S100 family | References |
|---|---|---|
| Pregnancy-associated with Down syndrome | Upregulated S100ß | 49 |
| IUGR | Upregulated S100ß | 50 |
| SGA babies SGA foetus | No change in S100ß | 51 |
| Pre eclampsia+IUGR | Upregulated S100ß | 52 |
| Miscarriage | Down regulated S100A11 | 53 |
| Up regulated S100A8, S100A9 | 4,47 | |
| Pre eclampsia | Up regulated S100ß | 52 |
| Pre-term labour | Up regulated S100ß | 51 |
| IVF failure | Down regulated S100A11, S100A10 | 54 |
| PCOS | Up regulated S100A12 | 55 |
| Endometriosis | Up regulated S100A4 | 56 |
| Endometriosis associated with infertility | Up regulated S100P | 56 |
| Gestational diabetes | Up regulated S100A9 | 57 |
IUGR, intrauterine growth restriction; SGA, small for gestational age; IVF, in vitro fertilization; PCOS, polycystic ovary syndrome