Table 3.
Estimates of Within-Person Variability for Albuminuria
| Albumin, mg/L |
UACR, mg/g |
|||
|---|---|---|---|---|
| First-Morning | Random | First-Morning | Random | |
| Median concentrationa | 68 [0.5–3813] | 108 [0.5–4,407] | 125 [1.3–3,557] | 1 73 [0.8–4,006] |
| Median CVw, %b | 33.2 (14.4–52.0) | 50.6 (39.0–62.3) | 32.5 (23.2–41.9) | 29.7 (19.5–40.0) |
| Median RCVpos | + 145% | +276% | + 141% | + 124% |
| Median RCVneg | –59% | –73% | –58% | –55% |
| Difference in median CVw vs random sampleb | –11.6 (–34.9 to 11.8) | — | +4.7 (–7.7 to 17.0) | — |
Abbreviations and definitions: CVw, within-person coefficient of variation; RCVpos and RCVneg, reference change values positive and negative, which refer to the percentage increase or decrease that must be exceeded between two sequential results for a change to be considered different at a significance level of 0.05; UACR, urinary albumin-creatinine ratio.
a
Based on first collected sample; values in brackets indicate range.
b
Values in parentheses are 95% confidence intervals.